This whole string of queries has unearthed way too many Mathias/Mathew Cain(e)s--some of whom have been mentioned in the string above.
At this point my head is swimming with them. Several stem from the line of Wm Caine 1710-1771/Ann Creer 1710-1764 of Marown

I'm still not certain about which Mathias Caine md Margaret Quark but believe he was b 1764 and is the one who died 10 Apr 1857 Onchan
Onchan MI
J 10
In memory of Margaret wife of Mathias Caine and
daughter of Daniel Quark of Ballacottier in this
parish who departed this life 29th August 1832
aged 53 years
Also of Mathias Caine of Douglas husband of the
above who departed this life 10th April 1857
aged 93 years
Also of two of their infant children