Posing by Donna Ref There is an extracted IGI entry for a Margaret Halsal ch 10 Jan 1744 d/o PATRICK Halsal
and a couple of patron submissions for ch 10 Jan 1745 d/o PATRICK Halsal and Isabel Quine

Donna, I think you may have solved this based on what you posted this family looks probable

Isabel Quine b 27 Feb 1724/3 daughter of John Quine
married Patrick 15 Feb 1742 Patrick Halsall
child Margaret Halsall
married William Quine married 16 Feb 1768

This looks a match for this family
John Quine d 1737
married Jane Quay
children
Thomas (Possibly married Cath Quirk?)
Ann
Jane
Isabel possibly b 27 Feb 1724/3 (possibly married 15 Feb 1742 Patrick Halsall)

That fits with these records
Margaret Halsall had an aunt Jane Quine alias Quay (Key)
Will 1754-3 E w QUINE Jane QUAY d 25 oct 1754;dau ann;niece margt halsall;only son thos exor

?Burial record Jane als QUAY widow of John QUINE from Pat buried German 25 Oct 1754

1737-2 E w QUINE John d 9 jun 1737;ch thomas(houses + land etc), ann(little croft), jane + isabel(ua) (daus jt exexs);wife jane als quay

1756-1 A 13 KEY Philip d 26 nov 1755;ballachrink;wife alive;wife's bro john garret;uncles pat key + Jon Kneal; lands of dauby mountain to heir;cousin john kneal;child margery ua supv Wm Garret (?fa-i-law)+ Wm Watterson; pledges john kneal + gilbert key;1778 magery at la friend Wm quine + Patrick Quilliam step-fa;inv
1756-2

Will 1808 A 97 HALSAL Isabel quine d 13 feb 1808;dau margt, cath quilliam exex; niece Isable Quine
[Possibly Isabel Quine who married Patrick Halsall in 1742 she was daughter of John Quine]