!MARRIAGE: 17 Nov 1821 Kirk Andreas Marriage Records FHL Film
#0106705 Lace Radcliffe son of William Radcliffe and Mary Martin married Esther Sayle daughter of William Sayle and Esther Radcliffe.
The mother Esther Radcliffe was the daughter of William Radcliffe and Margery Lace.
The above William Radcliffe/Mary Martin was the son of the same William Radcliffe and Margery Lace
So Lace Radcliffe and Esther Sayle are cousins I think.
There is a lot of info on the message board and Frances' marvelous Manx Note Book